TB-500:
A Research
Overview
TB-500 is a synthetic peptide corresponding to an active region of thymosin beta-4, a naturally occurring protein involved in regulating actin. It appears in preclinical literature on actin binding and cell migration. It holds no marketing authorisation and is supplied strictly for research use only.
What TB-500 is
TB-500 is a synthetic peptide that corresponds to an active region of thymosin beta-4 (often written Tβ4), a naturally occurring protein found in many tissues. Thymosin beta-4's principal known function is in the regulation of actin, one of the fundamental structural proteins inside cells. TB-500 represents the fragment of that protein most associated with actin binding in the literature.
It is supplied as a lyophilised powder for laboratory research, and requires reconstitution with a solvent such as bacteriostatic water before use in solution-phase research.
Background
Thymosin beta-4 is a well-characterised endogenous protein; TB-500 emerged as a research tool focused on the shorter active sequence rather than the full protein. It is studied predominantly in in-vitro and animal-model contexts.
TB-500 holds no marketing authorisation in any jurisdiction and has not been evaluated for safety or efficacy in humans. It is supplied strictly as a laboratory reference material, and no claim is made regarding any effect in people.
Areas of research interest
Research involving TB-500 and thymosin beta-4 concentrates on the actin cytoskeleton and cell movement:
- Actin binding — how the peptide interacts with actin, the protein it is best known for regulating.
- Cell migration models — laboratory systems studying how cells move.
- Angiogenesis and tissue models — themes it shares with other regenerative-research peptides.
These describe research activity, not effects established in humans.
Research context
TB-500 is frequently studied in the same regenerative-research literature as BPC-157, and the two are combined in our GLOW research preparation. What an accompanying certificate of analysis does and does not establish applies to TB-500 as to any other compound.
Frequently Asked Questions
TB-500 is a synthetic peptide corresponding to an active region of thymosin beta-4, a naturally occurring protein involved in regulating actin. It is supplied as a lyophilised powder for laboratory research use only.
TB-500 corresponds to the fragment of thymosin beta-4 most associated with actin binding in the research literature. Thymosin beta-4 is the full naturally occurring protein; TB-500 is a synthetic active-region peptide.
No. TB-500 holds no marketing authorisation and has not been evaluated for safety or efficacy in humans. It is supplied strictly as a laboratory reference material for research use only.